E.K.'s Band was a Ghanaian highlife band formed in 1949 by Emmanuel Kofi Nyame (also known as E.K. Nyame). The band was known for its fusion of traditional African rhythms with western music influences, creating a unique sound that was popular throughout Ghana and beyond.

E.K.'s Band released several works during its active years and was also selected to accompany the-then Ghanaian Prime Minister of Ghana to Liberia.

The band's music featured socially conscious lyrics and uplifting melodies that reflected the hopes and struggles of the Ghanaian people.

Nyame, the band leader, died in August 1977 and the band became inactive.

However, E.K.'s Band's music remains influential and continues to be celebrated by fans of highlife music in Ghana and beyond.

E.K.’s Band, was a Ghanaian band founded in 1952 and led by Ghanaian musician, Emmanuel Kofi Nyame (a.k.a. E.K Nyame).